Injectopedia™

Your curated hub for evidence-based injection techniques and cutting-edge advancements
in medical aesthetics–by industry experts.
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Illustration of upper and lower lip anatomy showing injection zones, vermilion tubercle, Cupid’s bow, philtral columns, oral commissures, and golden ratio landmarks for aesthetic lip augmentation.

Lip Augmentation

- Ghasemi S, Akbari Z;
Dent Clin North Am
July 2022

Transillumination images of rabbit ears comparing vascular occlusion after intra-arterial injection of PMMA vs. hyaluronic acid (HA), demonstrating significantly greater embolism risk and tissue necrosis with HA.

Risk Comparison of Filler Embolism Between Polymethyl Methacrylate (PMMA) and Hyaluronic Acid (HA)

- Nie F, Xie H, Wang G, An Y;
.Aesthetic Plast Surg
June 2019

Before-and-after image of a female patient treated for lower face aging, showing significant improvement in jawline, marionette lines, and chin contour following injection-based rejuvenation tailored to facial morphotype.

Contouring of Lower Face and Chin in Consideration of Facial Morphotypes and Shapes- Is it a More Accurate Approach?

- Yutskovskaya YA, Sergeeva AD, Kislitsyna AI, Landau M;
Madridge J Dermatol Res
Dec 2017

Facial anatomy illustration showing arterial supply to the chin and perioral region, including columellar, labial, mental, and submental arteries—key injection danger zones for aesthetic injectors.

Role of Nonsurgical Chin Augmentation in Full Face Rejuvenation: A Review and Our Experience

- Vanaman Wilson MJ, Jones IT, Butterwick K, Fabi SG;
Dermatol Surg
July 2018

Detailed illustration of midface anatomy showing facial fat compartments, vascular structures, retaining ligaments, and danger zones relevant for injectable filler safety, including infraorbital and angular arteries.

An approach to structural facial rejuvenation with fillers in women

- Fitzgerald R, Carqueville J, Yang PT;
Int J Womens Dermatol
Dec 2018

Chin marked with injection grid technique for botulinum toxin A treatment, part of a novel approach from Italian clinicians targeting dynamic dimpling and peau d’orange texture.

Chin imperfections: our experience with botulinum toxin A

- Corradino B, Lorenzo SD, Anna C, Cascino AP;
Aesthetic Medicine
April 2023

Facial filler injection mapping image showing midface aging lines and underlying skeletal injection sites, used in the dual plane technique for restoring facial volume at both deep and superficial levels.

Facial Rejuvenation with Fillers: The Dual Plane Technique

- Salti G, Rauso R;
Journal of Cutaneous and Aesthetic Surgery
Sept 2015

Facial injection mapping chart for male and female patients showing 3DD Lift treatment zones used in full-face rejuvenation with hyaluronic acid fillers and myomodulation techniques.

Myomodulation with Facial Fillers: A Comprehensive Technical Guide and Retrospective Case Series

- Coimbra DD, Stefanello B;
Aesth Plast Surg
June 2023

Anatomical Diagram of Intrascrotal Injection Sites for Botulinum Toxin A - Male Genital Aesthetic Techniques

Intrascrotal Injection of Botulinum Toxin A,
a Male genial Aesthetic Demand: Technique and Limits

- Ramelli E, Brault N, Tierny C, Atlan M, Cristofari S;
Prog Urol
May 2020

Anatomical dissection of the mentalis muscle and clinical photo of chin dimpling before botulinum toxin injection

Tips and Tricks for Facial Toxin Injections with Illustrated Anatomy

- Swift A, Green JB, Hernandez CA, Aguilera SB, Fagien S, Gold MH, Casabona G, Frank K, Nikolis A, Cotofana S;
Plast Reconstr Surg
Feb 2022

Cross-Sectional Anatomy of the Penis for Hyaluronic Acid Filler Augmentation - Male Genital Aesthetic Enhancement

Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome

- Zhang CL, Quan Y, Li H, Li Q, Bai WJ, Xu T, Zhang XW;
Asian J Androl
April 2022

Side-by-side comparison of a woman’s face showing the progression of vascular occlusion from Stage 1 (blanching) to Stage 5 (eschar formation) following hyaluronic acid filler injection.

Guideline for the Management of Hyaluronic Acid Filler-induced Vascular Occlusion

- Murray D, Convery C, Walker L, Et Al;
J Clin Aesthet Dermatol
May 2021

Anatomical gluteal mapping diagram for PLLA injections in male patients showing quadrant-based collagen stimulator distribution using the C-Tech method

Novel therapeutic approaches with poly-L-lactic acid for treating gluteal skin laxity in male patients

- Antony de Paula Barbosa, Alan Cristian Marinho Ferreira, Aline Castellar Duarte, Rafaella Vilela da Silva;
Chinese Journal of Plastic and Reconstructive Surgery
March 2025

Anatomical illustration showing injection sites for botulinum toxin (BoNTA) treatment of vaginismus, targeting the bulbospongiosus, pubococcygeus, and puborectalis muscles.

Botulinum toxin treatment of refractory vaginismus: a prospective study

- Desai SA, Shah B, Kroumpouzos G;
Int J Womens Dermatol
Nov 2024

Adverse Event: Dimpling Following Thread Lift - Clinical Case Study on Post-Procedure Complications in Aesthetic Medicine

Complications of thread lift about skin dimpling and thread extrusion

- Cheng-Kun Wang, PhD, MD;
Dermatologic Therapy
March 2020

Close-up of a patient’s cheek showing a visible dimple within a red dashed circle, indicating a common complication from facial thread lifting.

Facial Thread Lifting Complications

- Kyu-Ho Yi, Soo Yeon Park;
J Cosmet Dermatol
Jan 2025

Close-up of a lower face showing a visible calcium hydroxylapatite (CaHA) nodule in the jowl area, indicated by a black arrow.

Successful Treatment of Noninflammatory CaHA Nodules Using Focused Mechanical Vibration

- McCarthy AD, Berkowitz S, Chernoff WG;
Aesthet Surg J Open Forum
March 2024

Comparison of Penile Appearance Before and After Dermal Filler Augmentation - Study on Optimal Filler Choice for Male Genital Enhancement

Which Dermal Filler is Better for Penile Augmentation for Aesthetic Purposes? A Prospective, Single-Surgeon Study Based on Real-World Experience

- Kim DW, Jeong HC, Ko K, Yang DY, Kim JK, Lee SH, Kim TH, Lee WK;
World J Mens Health
April 2024

Close-up of a person’s face showing extreme swelling of the lips and cheeks, with a slightly parted mouth and visible nasal piercing—potentially indicating an adverse reaction to hyaluronic acid filler or hyaluronidase.

Guideline for the Safe Use of Hyaluronidase in Aesthetic Medicine, Including Modified High-dose Protocol

-Murray G, Convery C, Walker L, Davies E;
J Clin Aesthet Dermatol
Aug 2021

Close-up of the anterior neck showing multiple visible linear nodules after hyperdiluted calcium hydroxylapatite (CaHA) treatment.

Non-inflammatory nodule formation after hyperdiluted calcium hydroxyapatite treatment in the neck area

- Nipshagen MD, Velthuis PJ, Cook E, Mosmuller DGM;
Dermatol Ther
Sept 2020

Anatomical illustration of the cervical region highlighting muscle, vascular, and nerve structures, with a marked “Danger Zone” relevant for aesthetic and medical procedures.

Gold protocol: Combined treatment approach for neck rejuvenation with calcium hydroxyapatite, botulinum toxin, and hyaluronic acid

- de Sanctis Pecora C;
J Cosmet Dermatol
July 2024

Botulinum Toxin A (Botox) for Relieving Penile Retraction - Original Research on Male Genital Enhancement and Rejuvenation Techniques

Botulinum Toxin A (Botox) for Relieving Penile Retraction

-Osama Shaeer, Kamal Shaeer, Ahmad Shaeer;
The Journal of Sexual Medicine
Oct 2009

Complications of Injectables
in the Perioral Region

- Ben Talei MD;
Facial Plast Surg
2019

Filler-Induced Vascular Occlusion (FIVO) Craniofacial Arterial Map - Educational Graphic for Aesthetic Practitioners

Pathophysiology & Molecular Mechanisms of HA Filler-Induced Vascular Occlusion

- Danny J. Soares MD;
Molecules
August 2022

Illustrated classification of forehead wrinkle patterns and facial aging types, depicting Type I (Full), Type II (V-shaped), Type III (Central), and Type IV (Lateral).

A Novel, Customizable Injection Protocol for Treatment of the Forehead with IncobotulinumtoxinA

- Carla de Sanctus Pecora;
Clinical, Cosmetic & Investigational Dermatology
2020

Anatomical illustration of the lower eyelid and cheek region, highlighting the orbital malar ligament (OML) and the zygomatic cutaneous ligament (ZCL) in relation to festoons and malar bags.

Novel Approaches to the treatment of festoons

- Bradley S. Bloom, MD;
New York University School of Medicine

Illustrated depiction of facial overfilling complications, showing exaggerated aesthetic features such as “Flowerhorn Forehead,” “Chipmunk Cheeks,” “Duck Lips,” and “Witch Chin

exploring facial overfilled syndrome from the perspective of anatomy & the mismatched delivery of fillers

- Ting-Song Lim MD, Rungsima Wanitphakdeedecha MD, Kyu-Ho Yi MD PhD;
J Cosmet Dermatol
June 2024

Before-and-after comparison of a woman’s face showing the effects of botulinum toxin treatment on forehead lines, crow’s feet, and under-eye wrinkles.

Treating facial overfilled syndrome with impaired facial expression—Presenting clinical experience with ultrasound imaging

- Schelke L, Harris S, Cartier H,
Cotofana S, et al;
J Cosmet Dermatol
Dec 2023

Image of a patient’s buttocks with labeled treatment zones for upper pole lifting, central projection, and lateral expansion in non-surgical buttock augmentation

Glutaeal Remodelling Protocol: Volumization with Hyaluronic Acid & Collagen Biostimulation with Poly-L-Lactic Acid

- Faria G, Boggio R, Bellini M;
Skin Health Dis
April 2023

Close-up of a syringe injecting dermal filler into a person’s lips, demonstrating a cosmetic lip augmentation procedure.

from extreme to mainstream: the future of aesthetic injectables

- Leclerc O, Peters N, Scaglione A, Waring J;
McKinsey & Company
Dec 2021

Cadaveric dissection of the face highlighting key anatomical structures, including the orbicularis oris muscle (OOM), levator labii superioris alaeque nasi (LLSAN), and the transverse facial septum, relevant to facial overfilled syndrome.

Anatomy Behind Facial Overfilled Syndrome - The Transverse Facial Septum

- Cotofana S, Gotkin R,
Frank K, Et Al;
Dermatologic Surgery
Aug 2020

Infographic illustrating key success factors in medical aesthetics, including physician engagement, portfolio and pricing, and consumer engagement strategies.

The Right Moves to Make Now in Medical Aesthetics

- Rossi S, Orlova M;
BCG
July 2020

https://media.allergan.com/actavis/actavis/media/general/Moving%20the%20Needle%20on%20Ethics%20Book%20US.pdf

Moving the Needle on Aesthetics Ethics

- Allergan Aesthetics
May 2024

Aesthetic practitioner marking a patient’s crow’s feet area with a white pencil before administering botulinum toxin injections.

Medical Aesthetics Is Resilient, Growing, & Attracting Investors

- BCG
May 2023

Cover of the ISAPS 2023 Global Survey on Aesthetic and Cosmetic Procedures, featuring a close-up of a woman’s face with flowing hair.

ISAPS International Survey: Aesthetic/Cosmetic Procedures

- ISAPS
2023

Medical illustration by Dr Levent Efe (Certified Medical Illustrator) depicting needle aspiration during dermal filler injection and anatomical structures of the face, highlighting vascular and nerve pathways.

Aspiration Before Tissue Filler—An Exercise in Futility and Unsafe Practice

- Greg J Goodman, Mark R Magnusson, Peter Callan, Et Al;
Aesthetic Surgery Journal
Jan 2022

Close-up of a nodule extraction from the anterior neck following Poly-L-Lactic Acid (PLLA) injections, performed with forceps by a gloved medical professional.

Nodules on the Anterior Neck Following Poly-L-lactic Acid Injection

- Austin Dunn, Tyler Long, Matthew Zarraga, Shino Bay Aguilera;
Cutis
June 2022

Use of Botulinum Toxin for the Correction of Mild Ptosis

- Hamzah Mustak MD, Michael Rafaelof BS, Robert A. Goldberg MD, Daniel Rootman MD;
JCAD
April 2018

Medical illustration showing the skeletal anatomy of a female face in frontal and lateral views, highlighting crucial zygomatic and orbital landmarks used in aesthetic medicine.

Novel Anatomical Proposal for Botulinum Neurotoxin Injection Targeting Lateral Canthal Rhytids

- Kyu-Ho Yi, Ji-Hyun Lee, Ga-Young Kim, Et Al;
Toxins
July 2022

Before and after image of penile girth enhancement using PMMA dermal filler, showing increased volume and definition

Penile Girth Enhancement With Polymethylmethacrylate-Based Soft Tissue Fillers

-Casavantes L, Lemperle G, Morales P;
Journal of Sexual Medicine
July 2016

Side-by-side photos showing a female patient before and six weeks after triamcinolone injection to treat fibrotic tissue caused by hyaluronic acid filler in the nasolabial folds.

Fibrotic reaction to hyaluronic acid fillers in the face

- Peros I, Haneke El;
J Cosmet Dermatol
Aug 2024

Foreign Body Granulomas From Polymethylmethacrylate Treated Successfully with Allopurinol

Foreign Body Granulomas From Polymethylmethacrylate Treated Successfully with Allopurinol

- Reisberger E, Landthaler M, Wiest L, Schröder J, Stolz W;
Arch Dermatol
Jan 2003

Marked vector mapping on thighs and abdomen for Radiesse injections to treat skin flaccidity using a body vectoring technique.

Body vectoring technique with Radiesse® for tightening of the abdomen, thighs, and brachial zone

- Wasylkowski VC;
Clin Cosmet Investig Dermatol.
May 2015

Pie chart of six medical aesthetics consumer types—The One-Timer, Glam Extrovert, Deal Hunter, Reluctant Ager, Beauty Routiner, Growth Catalyst—used in Heddy injector training

The Six Types of Medical Aesthetic Consumers, And How to serve them all

- Sergio Rossi, Christine Barton, Andrea Agnolio, et al;
BCG
July 2024

Side-by-side comparison showing a woman before and six days after a PDO thread lift. The post-procedure image reveals pronounced indentations in both cheeks, characteristic of thread-related dimpling.

Facial Thread Lifting Complications in China: Analysis and Treatment

-Yi-Lin Li MD, Ze-Hui Li MM, Xue-Ying Chen MD;
Plastic and Reconstructive Surgery
Sept 2021

Facial mapping illustration showing temporal volume changes following masseter muscle treatment with incobotulinumtoxin type A.

Temporal volume increase after reduction of masseterichypertrophy utilizing incobotulinumtoxin type A

- Nikolis A, Enright KM, Rudolph C, Cotofana S;
J Cosmet Dermatol
June 2020

Extreme close-up of two diverse human eyes symbolizing patient individuality and introspection in the evolving field of medical aesthetics.

Here to stay: an attractive future for medical aesthetics

- Leigh Jansen, Olivier Leclerc, Nils Peters;
McKinsey & Company
Feb 2024

Infographic highlighting key statistics from the 2023 Stifel dermatology market report, including a $14.1B North American medspa market size, 3x increase in male procedures since 2000, and 3,000+ active medical spa clinics.

2023 Stifel Dermatology Market Overview

- Patrick Krause;
Stifel
Feb 2023

A Safe and Effective Lip Augmentation Method: The Step-by-Step Φ (Phi) Technique

-Keramidas E, Rodopoulou S, Gavala MI;;
Plast Reconstr Surg Glob Open
Feb 2021

Facial muscle injection guide showing muscles to inject and muscles to avoid, based on a nurse-authored study published in Plastic Surgical Nursing.

Consideration of Muscle Depth for Botulinum Toxin Injections: A Three-Dimensional Approach

-Kaplan JB;
Plast Surg Nurs
Jan 2017

The Clitoral Injection of IncobotulinumtoxinA for the Improvement of Arousal, Orgasm & Sexual Satisfaction- A Specific Method and the Effects on Women

-Runels C, Runnels A;
Journal of Women's Health Care
March 2024

The Current Preferred Female Lip Ratio

-Heidekrueger PI, Juran S, Szpalski C, Larcher L, Ng R, Broer PN;
J Craniomaxillofac Surg
Feb 2017

Comparing the Effects of Different Injection Techniques Used in Lip Augmentation on Filler Migration and Patient Satisfaction

-Buhsem O;
Cureus
July 2024

Influence of ethnicity on aesthetic preferences for lip characteristics in Caucasian male and female faces

-Kempa J, Alfertshofer M, Chua D, Domehri M, Akinsooto O, Antoszewski B, Timler W, Cotofana S, Kasielska-Trojan A;
J Plast Reconstr Aesthet Surg
Aug 2024

Is it possible to define the ideal lips?

-Kar M, Muluk NB, Bafaqeeh SA, Cingi C;
Acta Otorhinolaryngol Ital
Feb 2018

Botulinum Toxin—A Current Place in the Treatment of Chronic Migraine and Other Primary Headaches

-Kępczyńska K, Domitrz I;
Toxins
Sept 2022

Comparing the Effects of Different Injection Techniques Used in Lip Augmentation on Filler Migration and Patient Satisfaction

-de Maio M.;
Aesthetic Plast Surg
April 2021

Influence of ethnicity on aesthetic preferences for lip characteristics in Caucasian male and female faces

-Kempa J, Alfertshofer M, Chua D, Domehri M, Akinsooto O, Antoszewski B, Timler W, Cotofana S, Kasielska-Trojan A;
J Plast Reconstr Aesthet Surg
Aug 2024

Facial anatomy illustration featuring proprietary Heddy female injection mapping schema with overlaid “Coming Soon” text.

Coming soon...

African American male facial anatomy with proprietary injection mapping schema and “Coming Soon” overlay text.

coming soon..

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